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Evolution of the HUBER machine from 1980 to the HUBER System today!,
To this day, more stoppers are processed in the HUBER System than any
other processor.


COMPARISON OF OLD HUBER "CASSETTE DESIGN" TO
THE NEW HUBER System "OPEN DRUM DESIGN"
WITH PATENTED DIRECT IMPACT CLEANING + CIP + SIP

ORIGINAL CASSETTE SYSTEM (1980)           NEW TECHNOLOGY - OPEN DESIGN

Designed as a "carrousel" with pre-formed baskets mounted between the "rings" of the carousel. (baskets are stamped out of standard perforated S/S stock). No center spray bar. Sprays located on top and side. A complete drum with material transfer guides. Direct Spray center nozzle shaft, nozzles on the outside of the inner drum and the inside of the outer drum.
Efficiency of Particulate Reduction Level was up to 76% on the old cassette design. No Direct Impact Cleaning. No CIP or SIP. "Screen" effect masks water jets directed by rinsing nozzles. Problem with residual silicone deposits in dead "legs" of carrousel and "cone."

Efficiency of Particulate Reduction Level is up to 98% on the patented system when using Direct Impact Cleaning, CIP and SIP. High pressure sprays provide the essential shearing action needed to remove all deposits, particulates and pyrogens.

Uniform silicone distribution not possible due to restrictive cassette design. Stopper mass does allow proper silicone surfactant action to insure a smooth distribution along all stopper surfaces.  Uniform silicone distribution by gently separating the stoppers and cycling them through the silicone solution. The stoppers get individually "wetted" with emulsion. Repeatable and therefore validatable silicone film is consistently applied to the stopper surface.
Drying process does not eliminate clumping because of cassette containment. Causes moisture to be trapped in the stopper mass. Drying by HEPA filtered air. No centrifuge cycle possible in the cassette design. Drying process uses gentle movement of stoppers from product carrier to product carrier. Maximum surface exposure with 0.2 micron sterile filtered drying air. 
Cooling of mass of stoppers in each cassette needs longer cycle time. Cooling of intermittent shifted stoppers more effective with shorter cycle time.
Final Moisture Content with LOD method not better than 0.045 % . Final Moisture Content with LOD method is 0.015%
Pyrogen reduction is very restricted by "screen" effect and very inconsistent within the mass of stoppers in each cassette. Lack of shearing action with less than 12 nozzles allows pyrogens to remain on stopper surfaces, in blind stopper holes and on interior surfaces of the carousel, cassettes and the pressure vessel. Log 4 Pyrogen reduction guaranteed in the open drum design through shearing action applied through the high pressure jets on the stoppers. Direct spray impact cleaning of all mirror finished surfaces by more than 42 nozzles. This CIP cycle assures the maximum reduction of pyrogenic material.

Load/unload > 40 minutes

Load/unload 15 minutes

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Last modified on Friday, July 29, 2011
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